Although the morphology of various types of neurons
differs in some respects, they all contain four distinct regions with differing
functions: the cell body, the dendrites, the axon, and the axon
terminals.
Cell Body
The cell
body, or soma, contains the nucleus and is the
site of the synthesis of virtually all neuronal proteins and membranes. Some
proteins are synthesized in dendrites, but no proteins are made in axons
and axon terminals, which do not contain ribosomes. Proteins and
membranes that are required for renewal of the axon and nerve termini are
synthesized in the cell body and assembled there into membranous vesicles or
multiprotein particles by a process called anterograde transport. Transported
along microtubules down the length of the axon to the terminals,
these vesicles are inserted into the plasma membrane or other
organelles. Axonal microtubules are also the tracks along which damaged
membranes and organelles move up the axon toward the cell body; this process is
called retrograde transport [1]. Lysosomes,
where such material is degraded, are found only in the cell body.
In the CNS, neurons have extremely long dendrites with complex branches. This allows them to form synapses with and receive signals from a large number of other neurons. On the other hand, motor neurons and sensory neurons have long axons that can relay signals to and from the CNS.
Dendrite
Most neurons have multiple dendrites, which extend outward
from the cell body and are specialized to receive chemical signals from
the axon termini of other neurons. Dendrites convert these signals
into small electric impulses and transmit them in the
direction of the cell body.
Axon
Almost every neuron has a single axon. Axons are specialized for the conduction of action potential away
from the cell body toward the axon terminus generated as a result of
a sudden change in voltage. In a typical neuron, the action potential duration
is about a millisecond; when an action potential is not triggered, a neuron is
in a resting state.
Axon Terminal
An action potential is actively conducted down the axon
into the axon terminals,
small branches of the axon that form the synapses, or connections, with other
cells.
Axon Hillock
Axon hillock is the junction (joining) of the cell body and the
axon. It is also the site where an action potential originates.
Myelin Sheath
Myelin is a lipid-rich (fatty)
substance that surrounds the axons of some nerve
cells that act as insulation to increase
the rate at which signals/information (encoded as electrical impulses) is
passed along the axon. The myelin membranes
originate from and are a part of the Schwann cells in the PNS and the oligodendroglial cells in the
CNS.
General Features of a Neuron |
Reference:
Overview of Neuron Structure and Function. Khan Academy, https://www.khanacademy.org/science/biology/human-biology/neuron-nervous-system/a/overview-of-neuron-structure-and-function. Accessed 10 Jan. 2020.
Section 21.1 Overview of Neuron Structure and Function. Molecular Cell Biology. 4th Edition, NCBI, https://www.ncbi.nlm.nih.gov/books/NBK21535/. Accessed 10 Jan. 2020.
Campbell, et al. Biology: A Global Approach. 11th ed., Pearson, 2017.
Section 21.1 Overview of Neuron Structure and Function. Molecular Cell Biology. 4th Edition, NCBI, https://www.ncbi.nlm.nih.gov/books/NBK21535/. Accessed 10 Jan. 2020.
Campbell, et al. Biology: A Global Approach. 11th ed., Pearson, 2017.
沒有留言:
張貼留言